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Compare $PRAX vs $SYRE | Chartloom

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$PRAX vs $SYRE

Praxis Precision Medicines Inc · Spyre Therapeutics Inc

PRAX

Praxis Precision Medicines Inc

SYRE

Spyre Therapeutics Inc

Compare $PRAX vs $SYRE

Comparing Praxis Precision Medicines Inc and Spyre Therapeutics Inc

PRAXPraxis Precision Medicines Inc

SYRESpyre Therapeutics Inc

PRAXPraxis Precision Medicines Inc

Market cap

$7.24B

P/E (TTM)

—

Forward P/E (NTM)

—

Forward P/S (NTM)

67.04x

Rev growth (TTM)

—

YTD performance

-9.3%

52W performance

378.7%

FCF yield

-4.2%

SYRESpyre Therapeutics Inc

Market cap

$7.44B

P/E (TTM)

—

Forward P/E (NTM)

—

Forward P/S (NTM)

—

Rev growth (TTM)

—

YTD performance

180.2%

52W performance

384.7%

FCF yield

-2.8%

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Relative performance

Each ticker starts at 100. 110 means +10% from the start of this window — not a $110 share price.

PRAX

SYRE

Detailed metrics comparison

PRAX

Praxis Precision Medicines Inc

SYRE

Spyre Therapeutics Inc

Market Cap

PRAX$7.24B

SYRE$7.44B

Enterprise Value

PRAX$6.77B

SYRE$7.28B

Price

PRAX$259.86

SYRE$85.69

P/E Ratio

PRAXN/A

SYREN/A

P/S Ratio

PRAX964.65x

SYRE6,680.42x

EV/Sales

PRAX909.14x

SYRE0.00x

EV/EBITDA

PRAX0.00x

SYRE0.00x

P/B Ratio

PRAX6.15x

SYRE7.46x

P/FCF Ratio

PRAXN/A

SYREN/A

EV/FCF

PRAX-22.11x

SYRE-34.84x

PEG Ratio

PRAXN/A

SYREN/A

Forward P/E (NTM)

PRAXN/A

SYREN/A

Forward P/S (NTM)

PRAX67.04x

SYREN/A

Revenue (TTM)

PRAX$0

SYRE$0

Revenue Growth (YoY)

PRAXN/A

SYREN/A

Forward Rev Growth

PRAX38349.0%

SYRE231.1%

Gross Margin (TTM)

PRAX0.0%

SYRE0.0%

Operating Margin (TTM)

PRAX0.0%

SYRE0.0%

EBITDA Margin (TTM)

PRAX0.0%

SYRE0.0%

Net Margin (TTM)

PRAX0.0%

SYRE0.0%

FCF Margin (TTM)

PRAXN/A

SYREN/A

Net Income (TTM)

PRAX$-255M

SYRE$-179M

FCF (TTM)

PRAX$-306M

SYRE$-209M

EPS (TTM)

PRAX$0.00

SYRE-$2.11

ROE (TTM)

PRAX-4302.0%

SYRE-2432.0%

ROA (TTM)

PRAX-4022.0%

SYRE-2223.0%

ROIC (TTM)

PRAX-4302.0%

SYRE-2432.0%

Cash

PRAX$475M

SYRE$162M

Debt

PRAX$0

SYRE$0

Net Cash/Debt

PRAX$475M

SYRE$162M

Current Ratio (TTM)

PRAX15.73x

SYRE18.53x

Quick Ratio (TTM)

PRAX15.46x

SYRE18.09x

Debt/Equity (TTM)

PRAX0.00x

SYRE0.00x

Debt/Assets (TTM)

PRAX0.0%

SYRE0.0%

Interest Coverage (TTM)

PRAXN/A

SYREN/A

Net Debt/EBITDA (TTM)

PRAX0.00x

SYRE0.00x

Beta

PRAX2.88

SYRE3.19

52W Performance

PRAX378.7%

SYRE384.7%

YTD Performance

PRAX-9.3%

SYRE180.2%

% from 52W High

PRAX-33.8%

SYRE-22.2%

% from 52W Low

PRAX414.0%

SYRE385.5%

Asset Turnover (TTM)

PRAX0.02x

SYRE0.01x

FCF Yield (TTM)

PRAX-4.2%

SYRE-2.8%

Earnings Yield (TTM)

PRAX-3.5%

SYRE-2.4%

Dividend Yield (TTM)

PRAXN/A

SYREN/A

Rule of 40

PRAX0.0

SYRE0.0

EV/GP/RG

PRAXN/A

SYREN/A

Ticker research

View PRAX research View SYRE research

Metric	PRAX Praxis Precision Medicines Inc	SYRE Spyre Therapeutics Inc
Market & Valuation
Market Cap	$7.24B	$7.44B
Enterprise Value	$6.77B	$7.28B
Price	$259.86	$85.69
P/E Ratio	N/A	N/A
P/S Ratio	964.65x	6,680.42x
EV/Sales	909.14x	0.00x
EV/EBITDA	0.00x	0.00x
P/B Ratio	6.15x	7.46x
P/FCF Ratio	N/A	N/A
EV/FCF	-22.11x	-34.84x
PEG Ratio	N/A	N/A
Forward P/E (NTM)	N/A	N/A
Forward P/S (NTM)	67.04x	N/A
Revenue & Growth
Revenue (TTM)	$0	$0
Revenue Growth (YoY)	N/A	N/A
Forward Rev Growth	38349.0%	231.1%
Profitability
Gross Margin (TTM)	0.0%	0.0%
Operating Margin (TTM)	0.0%	0.0%
EBITDA Margin (TTM)	0.0%	0.0%
Net Margin (TTM)	0.0%	0.0%
FCF Margin (TTM)	N/A	N/A
Net Income (TTM)	$-255M	$-179M
FCF (TTM)	$-306M	$-209M
EPS (TTM)	$0.00	-$2.11
ROE (TTM)	-4302.0%	-2432.0%
ROA (TTM)	-4022.0%	-2223.0%
ROIC (TTM)	-4302.0%	-2432.0%
Financial Health
Cash	$475M	$162M
Debt	$0	$0
Net Cash/Debt	$475M	$162M
Current Ratio (TTM)	15.73x	18.53x
Quick Ratio (TTM)	15.46x	18.09x
Debt/Equity (TTM)	0.00x	0.00x
Debt/Assets (TTM)	0.0%	0.0%
Interest Coverage (TTM)	N/A	N/A
Net Debt/EBITDA (TTM)	0.00x	0.00x
Performance
Beta	2.88	3.19
52W Performance	378.7%	384.7%
YTD Performance	-9.3%	180.2%
% from 52W High	-33.8%	-22.2%
% from 52W Low	414.0%	385.5%
Efficiency & Yields
Asset Turnover (TTM)	0.02x	0.01x
FCF Yield (TTM)	-4.2%	-2.8%
Earnings Yield (TTM)	-3.5%	-2.4%
Dividend Yield (TTM)	N/A	N/A
Other
Rule of 40	0.0	0.0
EV/GP/RG	N/A	N/A
Ticker research	View PRAX research	View SYRE research

Valuation

P/S Ratio

PRAX

964.65x

SYRE

6,680.42x

EV/FCF

SYRE

-34.84x

PRAX

-22.11x

Growth & revenue

Forward Revenue Growth

PRAX

38349.0%

SYRE

231.1%

Profitability & performance

Gross Margin

PRAX

0.0%

SYRE

0.0%

ROE

SYRE

-2432.0%

PRAX

-4302.0%

FCF Yield %

SYRE

-2.8%

PRAX

-4.2%

52-Week Performance

SYRE

384.7%

PRAX

378.7%

Detailed metrics comparison

PRAX

Praxis Precision Medicines Inc

SYRE

Spyre Therapeutics Inc

Market Cap

PRAX$7.24B

SYRE$7.44B

Enterprise Value

PRAX$6.77B

SYRE$7.28B

Price

PRAX$259.86

SYRE$85.69

P/E Ratio

PRAXN/A

SYREN/A

P/S Ratio

PRAX964.65x

SYRE6,680.42x

EV/Sales

PRAX909.14x

SYRE0.00x

EV/EBITDA

PRAX0.00x

SYRE0.00x

P/B Ratio

PRAX6.15x

SYRE7.46x

P/FCF Ratio

PRAXN/A

SYREN/A

EV/FCF

PRAX-22.11x

SYRE-34.84x

PEG Ratio

PRAXN/A

SYREN/A

Forward P/E (NTM)

PRAXN/A

SYREN/A

Forward P/S (NTM)

PRAX67.04x

SYREN/A

Revenue (TTM)

PRAX$0

SYRE$0

Revenue Growth (YoY)

PRAXN/A

SYREN/A

Forward Rev Growth

PRAX38349.0%

SYRE231.1%

Gross Margin (TTM)

PRAX0.0%

SYRE0.0%

Operating Margin (TTM)

PRAX0.0%

SYRE0.0%

EBITDA Margin (TTM)

PRAX0.0%

SYRE0.0%

Net Margin (TTM)

PRAX0.0%

SYRE0.0%

FCF Margin (TTM)

PRAXN/A

SYREN/A

Net Income (TTM)

PRAX$-255M

SYRE$-179M

FCF (TTM)

PRAX$-306M

SYRE$-209M

EPS (TTM)

PRAX$0.00

SYRE-$2.11

ROE (TTM)

PRAX-4302.0%

SYRE-2432.0%

ROA (TTM)

PRAX-4022.0%

SYRE-2223.0%

ROIC (TTM)

PRAX-4302.0%

SYRE-2432.0%

Cash

PRAX$475M

SYRE$162M

Debt

PRAX$0

SYRE$0

Net Cash/Debt

PRAX$475M

SYRE$162M

Current Ratio (TTM)

PRAX15.73x

SYRE18.53x

Quick Ratio (TTM)

PRAX15.46x

SYRE18.09x

Debt/Equity (TTM)

PRAX0.00x

SYRE0.00x

Debt/Assets (TTM)

PRAX0.0%

SYRE0.0%

Interest Coverage (TTM)

PRAXN/A

SYREN/A

Net Debt/EBITDA (TTM)

PRAX0.00x

SYRE0.00x

Beta

PRAX2.88

SYRE3.19

52W Performance

PRAX378.7%

SYRE384.7%

YTD Performance

PRAX-9.3%

SYRE180.2%

% from 52W High

PRAX-33.8%

SYRE-22.2%

% from 52W Low

PRAX414.0%

SYRE385.5%

Asset Turnover (TTM)

PRAX0.02x

SYRE0.01x

FCF Yield (TTM)

PRAX-4.2%

SYRE-2.8%

Earnings Yield (TTM)

PRAX-3.5%

SYRE-2.4%

Dividend Yield (TTM)

PRAXN/A

SYREN/A

Rule of 40

PRAX0.0

SYRE0.0

EV/GP/RG

PRAXN/A

SYREN/A

Ticker research

View PRAX research View SYRE research

Metric	PRAX Praxis Precision Medicines Inc	SYRE Spyre Therapeutics Inc
Market & Valuation
Market Cap	$7.24B	$7.44B
Enterprise Value	$6.77B	$7.28B
Price	$259.86	$85.69
P/E Ratio	N/A	N/A
P/S Ratio	964.65x	6,680.42x
EV/Sales	909.14x	0.00x
EV/EBITDA	0.00x	0.00x
P/B Ratio	6.15x	7.46x
P/FCF Ratio	N/A	N/A
EV/FCF	-22.11x	-34.84x
PEG Ratio	N/A	N/A
Forward P/E (NTM)	N/A	N/A
Forward P/S (NTM)	67.04x	N/A
Revenue & Growth
Revenue (TTM)	$0	$0
Revenue Growth (YoY)	N/A	N/A
Forward Rev Growth	38349.0%	231.1%
Profitability
Gross Margin (TTM)	0.0%	0.0%
Operating Margin (TTM)	0.0%	0.0%
EBITDA Margin (TTM)	0.0%	0.0%
Net Margin (TTM)	0.0%	0.0%
FCF Margin (TTM)	N/A	N/A
Net Income (TTM)	$-255M	$-179M
FCF (TTM)	$-306M	$-209M
EPS (TTM)	$0.00	-$2.11
ROE (TTM)	-4302.0%	-2432.0%
ROA (TTM)	-4022.0%	-2223.0%
ROIC (TTM)	-4302.0%	-2432.0%
Financial Health
Cash	$475M	$162M
Debt	$0	$0
Net Cash/Debt	$475M	$162M
Current Ratio (TTM)	15.73x	18.53x
Quick Ratio (TTM)	15.46x	18.09x
Debt/Equity (TTM)	0.00x	0.00x
Debt/Assets (TTM)	0.0%	0.0%
Interest Coverage (TTM)	N/A	N/A
Net Debt/EBITDA (TTM)	0.00x	0.00x
Performance
Beta	2.88	3.19
52W Performance	378.7%	384.7%
YTD Performance	-9.3%	180.2%
% from 52W High	-33.8%	-22.2%
% from 52W Low	414.0%	385.5%
Efficiency & Yields
Asset Turnover (TTM)	0.02x	0.01x
FCF Yield (TTM)	-4.2%	-2.8%
Earnings Yield (TTM)	-3.5%	-2.4%
Dividend Yield (TTM)	N/A	N/A
Other
Rule of 40	0.0	0.0
EV/GP/RG	N/A	N/A
Ticker research	View PRAX research	View SYRE research