Obsidian Therapeutics Inc. engages in developing cell and gene therapies, particularly for the treatment of solid tumors and cancer. The company is headquartered in Bedford, Massachusetts and currently employs 3 full-time employees. Its proprietary cytoDRiVE technology is designed to regulate the timing and level of protein function by using FDA-approved small-molecule drugs. Its lead clinical program, OBX-115, is an investigational TIL cell therapy engineered to express membrane-bound IL15 (mbIL15), which is designed to support TIL activity. Its cytoDRiVE discovery platform has identified a library of internally discovered drug-responsive domains (DRDs) of varying sizes and intended purposes and enables rapid optimization of regulatable and functional proteins in any cell type. The company has developed a synthetic biology engineering toolkit that supports the design and optimization of a range of therapeutic proteins, including but not limited to type I/II membrane proteins, and membrane-bound cytokines.
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